teeter@bcchme.bc.edu; teeter@bc.edu; web address: http://www2.bc.edu/~teeter/Courses/CH584/CH584.html
X-ray crystallography provides a unique look at the three-dimensional architecture of molecules. This course will deal with single crystal X-ray diffraction analysis of primarily small molecules with mention of problems of larger structures and macromolecules. Both practical and theoretical aspects of structure analysis will be stressed. Subjects include crystal growth, crystal lattices and space groups, production and diffraction of X-rays, crystal structure solution, least squares refinement, analysis of structures, computer graphic display of structures, and analysis of structures. Exercises and problem sets will supplement the lectures.
Crystal Structure Analysis for Chemists and Biologists. J. Glusker, M. Rossi, M. Lewis. (1994)
Crystal Structure Analysis: A Primer. J. Glusker & K. Trueblood.
X-ray Structure Determination: A Practical Guide. G. Stout & L. Jensen.
Principles of Protein X-ray Crystallography. J. Drenth.
Crystallography 101 - Index, a web tutorial covering many topics of this course.
X-ray Diffraction, an overview.
Teaching Guide to X-ray and Neutron Diffraction, some use of fourier transforms.
Kevin Cowtan's Picture Book of Fourier Transforms, whimsical with real life images.
What is a crystal?
Crystal Growing Guide, graduate student oriented.
Quizzes (5%), exams (40%), problem sets & exercises (25%), final exam (30%).
For notes about homework, please look here. Homework Notes
Last updated August 29, 1997