our logo depicts the chemical
makeup of the neuropeptides
studied in the lab
Higgins Lab
winter view of Boston College Campus

Publications and Resources

List of publications
2013

Dumais KM, Bredewold R, Mayer TE, Veenema AH. Sex differences in oxytocin receptor binding in forebrain regions: correlations with social interest in brain region- and sex-specific ways. Hormones & Behavior, 64:693-701.

Veenema AH, Bredewold R, De Vries GJ. Sex-specific modulation of juvenile social play by vasopressin. Psychoneuroendocrinology, 38:2554-61.

Lukas M, Toth I, Veenema AH, Neumann ID. Oxytocin mediates rodent social memory within the lateral septum and the medial amygdala depending on the relevance of the social stimulus: Male juvenile versus female adult conspecifics. Psychoneuroendocrinology, 38:916-26.

2012

Beiderbeck DI, Reber SO, Havasi A, Bredewold R, Veenema AH, Neumann ID. High and abnormal forms of aggression in rats with extremes in trait anxiety - Involvement of the dopamine system in the nucleus accumbens. Psychoneuroendocrinology, 37:1969-80.

Taylor PV, Veenema AH, Paul MJ, Bredewold R, Isaacs S, de Vries GJ. Sexually dimorphic effects of a prenatal immune challenge on social play and vasopressin expression in juvenile rats. Biology of Sex Differences, Jun 14;3(1):15.

de Vries GJ, Veenema AH, Brown CH. Vasopressin and oxytocin: keys to understanding the neural control of physiology and behaviour. J Neuroendocrinol, 24:527.

Veenema AH. Toward understanding how early-life social experiences alter oxytocin- and vasopressin-regulated social behaviors. Hormones & Behavior, 61:304-12.

Veenema AH, Bredewold R, De Vries GJ. Vasopressin regulates social recognition in juvenile and adult rats of both sexes, but in sex- and age-specific ways. Hormones & Behavior, 61:50-6.

2011

Lukas M, Toth I, Reber SO, Slattery DA, Veenema AH, Neumann ID. The neuropeptide oxytocin facilitates pro-social behavior and prevents social avoidance in rats and mice. Neuropsychopharmacology, 36:2159-68.

Lukas M, Bredewold R, Landgraf R, Neumann ID, Veenema AH. Early life stress impairs social recognition due to a blunted response of vasopressin release within the septum of adult male rats. Psychoneuroendocrinology, 36:843-853.

2010

Neumann ID, Veenema AH, Beiderbeck DI. Aggression and anxiety: social context and neurobiological links. Front Behav Neurosci, Mar 30;4:12.

Veenema AH, Beiderbeck DI, Lukas M, Neumann ID. Distinct correlations of vasopressin release within the lateral septum and the bed nucleus of the stria terminalis with the display of intermale aggression. Horm Behav, 58:273-281.

Lukas M, Bredewold R, Neumann ID, Veenema AH. Maternal separation interferes with the development of vasopressin and oxytocin receptors in the brain. Neuropharmacology, 58:78-87.

2009

Veenema AH. Early life stress, the development of aggression and neurobiological correlates: What can we learn from animal models? Front Neuroendocrinol, 30:497–518.

Veenema AH, Neumann ID. Maternal separation enhances offensive play-fighting in juvenile male rats. Psychoneuroendocrinology, 23:463-467.

2008

Veenema AH, Neumann ID. Role of central vasopressin and oxytocin release in social behaviours. Prog Brain Res, 170:261-276.

Veenema AH, Reber SO, Selch S, Obermeier F, Neumann ID. Early life stress enhances the vulnerability to chronic psychosocial stress and experimental colitis in adult mice. Endocrinology, 149:2727-2736.

Reber SO, Obermeier F, Straub HR, Veenema AH, Neumann ID. Chronic psychosocial stress (subordinate colony housing) increases the severity of a DSS-induced colitis in mice – implications and mechanisms. Stress, 11:225-234.

2007

Beiderbeck DI, Neumann ID, Veenema AH. Differences in intermale aggression are accompanied by opposite vasopressin release patterns within the septum in rats bred for high and low anxiety. Eur J Neurosci, 26:3597-3605.

Veenema AH, Neumann ID. Neurobiological mechanisms of aggression and stress coping: a comparative study in mouse and rat selection lines. Brain Behav Evol, 70:274-285.

Veenema AH, de Kloet ER, de Wilde MC, Roelofs AJ, Kawata M, Buwalda B, Neumann ID, Koolhaas JM, Lucassen PJ. Differential effects of stress on adult hippocampal cell proliferation in low and high aggressive mice. J Neuroendocrinol, 19:489-498.

Veenema AH, Bredewold R, Neumann ID. Opposite effects of maternal separation on intermale and maternal aggression in C57Bl/6 mice: link to hypothalamic vasopressin and oxytocin immunoreactivity. Psychoneuroendocrinology, 32:437-50.

Reber SO, Birkeneder L, Veenema AH, Obermeier F, Falk W, Straub RH, Neumann ID. Adrenal insufficiency and colonic inflammation following a novel chronic psycho-social stress paradigm in mice: implications and mechanisms. Endocrinology, 148:670-82.

Veenema AH, Torner L, Blume A, Beiderbeck DI, Neumann ID. Low inborn anxiety correlates with high intermale aggression: Link to ACTH response and neuronal activation of the hypothalamic paraventricular nucleus. Horm Behav, 51:11-19.

2006

Veenema AH, Blume A, Niederle D, Buwalda B, Neumann ID. Effects of early life stress on adult male aggression and hypothalamic vasopressin and serotonin. Eur J Neurosci, 24:1711-20.

Feldker DE, Morsink MC, Veenema AH, Datson NA, Proutski V, Lathouwers D, de Kloet ER, Vreugdenhil E. The effect of chronic exposure to highly aggressive mice on hippocampal gene expression of non-aggressive subordinates. Brain Res, 1089:10-20.

Neumann ID, Torner L, Toschi N, Veenema AH. Oxytocin actions within the supraoptic and paraventricular nuclei: differential effects on peripheral and intranuclear vasopressin release. Am J Physiol Regul Integr Comp Physiol, 291:R29-36.

2005

Veenema AH, Sijtsma B, Koolhaas JM, De Kloet ER. The stress response to sensory contact in mice: genotype effect of the stimulus animal. Psychoneuroendocrinology, 30:550-557.

Veenema AH, Cremers TIFH, Jongsma M, Steenbergen P, De Boer SF, De Kloet ER, Koolhaas JM. Differential effects of two 5-HT1a receptor agonists on forced swimming behaviour and 5-HT metabolism in low and high aggressive mice. Psychopharmacology, 178:151-160.

Buwalda B, Kole MHP, Veenema AH, Huininga M, De Boer SF, Korte SM, Koolhaas JM. Long-term effects of social stress on brain and behavior: a focus on hippocampal functioning. Neurosci Biobehav Rev, 29:83-97.

2004

Veenema AH, Koolhaas JM, De Kloet ER. Basal and stress-induced differences in HPA axis, 5-HT responsiveness and hippocampal cell proliferation in two mouse lines. Ann N Y Acad Sci, 1018: 255-265.

2003

Feldker DEM, Datson NA, Veenema AH, Proutski V, Lathouwers D, De Kloet ER, Vreugdenhil E. GeneChip analysis of hippocampal gene expression profiles of short- and long-attack-latency mice: technical and biological implications. J Neuroscience Res, 74:701-716.

Sluyter F, Arseneault L, Moffitt TE, Veenema AH, de Boer SF, Koolhaas JM. Towards an animal model for antisocial behavior: parallels between mice and men. Behav Genet, 33:563-574.

Veenema AH, Meijer OC, De Kloet ER, Koolhaas JM. Genetic selection for coping style predicts stressor susceptibility. J Neuroendocrinol, 15:256-267.

Veenema AH, Meijer OC, De Kloet ER, Koolhaas JM, Bohus BG. Differences in basal and stress-induced HPA regulation of wild house mice selected for high and low aggression. Horm Behav, 43:197-204.

Feldker DE, Datson NA, Veenema AH, Meulmeester E, De Kloet ER, Vreugdenhil E. Serial analysis of gene expression predicts structural differences in hippocampus of long attack latency and short attack latency mice. Eur J Neurosci, 17:379-387.

2002

Van Riel E, Meijer OC, Veenema AH, Joëls M. Hippocampal serotonin responses in short and long attack latency mice. J Neuroendocrinol, 14:234-239.

2000

Abraham I, Harkany T, Horvath KM, Veenema AH, Penke B, Nyakas C, Luiten PG. Chronic corticosterone administration dose-dependently modulates Abeta(1-42)- and NMDA-induced neurodegeneration in rat magnocellular nucleus basalis. J Neuroendocrinol, 12:486-94.

1997

Abraham I, Veenema AH, Nyakas C, Harkany T, Bohus BG, Luiten PG. Effect of corticosterone and adrenalectomy on NMDA-induced cholinergic cell death in rat magnocellular nucleus basalis. J Neuroendocrinol, 9:713-720.